Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8344463 | 0.79 | IDO1 (0.50) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| SCHEMBL27684284 | 0.78 | CYP3A4 (0.53) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| SCHEMBL26666217 | 0.75 | NPC1 (0.59) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| SCHEMBL10066877 | 0.73 | CYP3A4 (0.54) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| SCHEMBL12075147 | 0.73 | CCR1 (0.59) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| SCHEMBL12075555 | 0.72 | LMNA (0.53) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| Phenanthroline SCHEMBL29367277 | 0.72 | CCR1 (1.00) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| Phenanthroline SCHEMBL29354015 | 0.72 | CCR1 (1.00) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| Phenanthroline SCHEMBL8845760 | 0.72 | CCR1 (1.00) | CYP3A4CYP2D6TDP1ALOX15LMNA | |
| Phenanthroline SCHEMBL8312 | 0.72 | CCR1 (1.00) | CYP3A4CYP2D6TDP1ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491987-B | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2014-06-11 | — | — | CN | claimed |
| CN-102491987-A | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2012-06-13 | — | — | CN | claimed |
| CN-106010502-A | Preparation method of rare earth mesoporous hybrid luminescent material with fluorine ion sensing properties | 河北科技大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-102491987-B | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2014-06-11 | — | — | CN | disclosed |
| CN-102491987-A | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2012-06-13 | — | — | CN | disclosed |