Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832255 | 0.84 | KDM1A (0.39) | MRGPRX4BRD4TYRNPC1 | |
| SCHEMBL27856528 | 0.79 | LMNA (0.36) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL27461034 | 0.76 | TDP1 (0.52) | MRGPRX4BRD4ALDH1A1RXRATDP1 | |
| SCHEMBL28791646 | 0.74 | MEN1 (0.41) | ALDH1A1MEN1KMT2ATYRKDM4E | |
| SCHEMBL1115032 | 0.74 | PTPN1 (0.61) | MRGPRX4BRD4ALDH1A1RXRASGMS2 | |
| SCHEMBL7539452 | 0.73 | LMNA (0.51) | MRGPRX4BRD4ALDH1A1RXRATDP1 | |
| SCHEMBL27832260 | 0.72 | TYR (0.36) | MEN1KMT2ATYR | |
| SCHEMBL27686665 | 0.72 | TDP1 (0.49) | MRGPRX4BRD4ALDH1A1RXRATDP1 | |
| SCHEMBL27856531 | 0.72 | AMY1A (0.40) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27856583 | 0.71 | MEN1 (0.41) | ALDH1A1MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448937-A | Aryl Substituted Carboxamide Derivatives As Calcium Or Sodium Channel Blockers | RAQUALIA PHARMA INC | 2012-05-09 | — | — | CN | disclosed |