Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993464 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KDM4EMAPTKMT2A | |
| Ethyl Isonicotinate SCHEMBL24935 | 0.79 | CA12 (0.62) | NAMPTALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL28255636 | 0.79 | GAA (0.50) | NAMPTSMN1; SMN2ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL28052061 | 0.79 | SOAT1 (0.47) | NAMPTSMN1; SMN2ALDH1A1KDM4EMAPT | |
| Ethyl Isonicotinate SCHEMBL11194007 | 0.78 | CA12 (0.60) | NAMPTALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29202940 | 0.77 | KDM4E (0.48) | SMN1; SMN2ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL19439269 | 0.76 | HSD17B10 (0.50) | SMN1; SMN2ALDH1A1KDM4EMAPTLMNA | |
| Urethane SCHEMBL27856564 | 0.76 | ALOX15 (0.48) | NAMPTSMN1; SMN2ALDH1A1KDM4EMAPT | |
| Ethyl Isonicotinate SCHEMBL10545892 | 0.73 | CA12 (0.55) | NAMPTSMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL647632 | 0.73 | HSD17B10 (0.64) | SMN1; SMN2ALDH1A1KDM4EKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102369202-A | Azaquinolinone derivatives and uses thereof | LINK MEDICINE CORP | 2012-03-07 | — | — | CN | disclosed |