Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873817 | 0.94 | PARP1 (0.47) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL27857096 | 0.83 | DDAH1 (0.53) | — | |
| SCHEMBL6755253 | 0.83 | PARP1 (0.54) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| Bromide SCHEMBL28178865 | 0.82 | DDAH1 (0.51) | — | |
| SCHEMBL3857633 | 0.78 | PARP1 (0.49) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL6753970 | 0.78 | PARP1 (0.49) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL6757219 | 0.77 | PARP1 (0.48) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL6753976 | 0.77 | PARP1 (0.48) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL6756154 | 0.77 | PARP1 (0.48) | PARP1POLBPI4KAPI4K2BPI4K2A | |
| SCHEMBL6753951 | 0.77 | PARP1 (0.48) | PARP1POLBPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491344-B | Silica nano-particle and preparation method and use thereof | UNIV KUNMING SCIENCE & TECHNOLOGY | 2014-04-02 | — | — | CN | claimed |
| CN-102491344-A | Silica nano-particle and its preparation method and use | UNIV KUNMING SCIENCE & TECHNOLOGY | 2012-06-13 | — | — | CN | claimed |
| CN-107074015-B | Rubber composition for tire, pneumatic tire, and non-pneumatic tire | 住友橡胶工业株式会社 | 2019-12-06 | — | — | CN | disclosed |
| CN-102491344-B | Silica nano-particle and preparation method and use thereof | UNIV KUNMING SCIENCE & TECHNOLOGY | 2014-04-02 | — | — | CN | disclosed |
| CN-102491344-A | Silica nano-particle and its preparation method and use | UNIV KUNMING SCIENCE & TECHNOLOGY | 2012-06-13 | — | — | CN | disclosed |