Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LIPA | P38571 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399580 | 0.74 | ALDH1A1 (0.45) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL29124849 | 0.74 | ALDH1A1 (0.45) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL26614382 | 0.71 | ALDH1A1 (0.42) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL5750257 | 0.71 | ALDH1A1 (0.47) | ALDH1A1POLBHSD11B1LIPASMN1; SMN2 | |
| SCHEMBL27597212 | 0.71 | — | — | |
| SCHEMBL3316653 | 0.70 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL16512381 | 0.70 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL9987783 | 0.70 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL12481132 | 0.70 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT | |
| SCHEMBL304391 | 0.70 | ALDH1A1 (0.50) | ALDH1A1POLBHSD11B1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959882-B | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-102510865-A | Nitrogen-containing spiro compound and pharmaceutical use thereof | JAPAN TOBACCO INC | 2012-06-20 | — | — | CN | disclosed |