Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175202 | 0.80 | LOXL2 (0.46) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL2175963 | 0.80 | ALDH1A1 (0.45) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL7505756 | 0.80 | ALDH1A1 (0.45) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL1542502 | 0.80 | ALDH1A1 (0.45) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL8351207 | 0.80 | PDE10A (0.48) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL27609855 | 0.77 | PDE10A (0.46) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL901810 | 0.77 | HRH1 (0.50) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL14911641 | 0.77 | PDE10A (0.46) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL19700908 | 0.76 | PDE10A (0.42) | ALDH1A1PDE10ACYP3A4MAPTKDM4E | |
| SCHEMBL14518833 | 0.76 | PDE10A (0.42) | ALDH1A1PDE10ACYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015651-A | Compounds and compositions as TLR activity modulators | IRM LLC | 2011-04-13 | — | — | CN | disclosed |