SCHEMBL27858232

SCHEMBL27858232

CC1(C)O[Si](C)(C)CC(c2ccccc2)C1(C)C

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 19/20 0.43
MAOA P21397 18/20 0.43
MAOB P27338 18/20 0.43
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28429200 0.74 KDM1A (0.40) KDM1AMAOAMAOB
SCHEMBL27476971 0.68 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL28577296 0.67 KDM1A (0.41) KDM1AMAOAMAOB
SCHEMBL8320758 0.66 MAOA (0.42) KDM1AMAOAMAOB
SCHEMBL626573 0.65 KDM1A (0.36) KDM1AMAOAMAOB
SCHEMBL4331068 0.64 KDM1A (0.67) KDM1AMAOAMAOB
Cyanide SCHEMBL27790784 0.63 KDM1A (0.59) KDM1AMAOAMAOB
SCHEMBL6573456 0.63 TSHR (0.35)
Ammonia Solution, Strong SCHEMBL11017865 0.62 KDM1A (0.64) KDM1AMAOAMAOB
SCHEMBL27615490 0.62 KDM1A (0.52) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108138181-A RNA complex for inhibiting melanin production 奥利克斯医药有限公司 2018-06-08 CN disclosed
CN-101442908-B The tick of preparation and insect repellent composition 纳幕尔杜邦公司 2016-09-28 CN disclosed
CN-104188833-A AQUEOUS COMPOSITION SUITABLE AS SHAMPOO RHODIA OPERATIONS 2014-12-10 CN disclosed
CN-102246014-A Zinc oxide aqueous and non-aqueous dispersions KOBO PRODUCTS INC 2011-11-16 CN disclosed