SCHEMBL626573

SCHEMBL626573

CC1(O[SiH3])O[Si](c2ccccc2)(c2ccccc2)CC(c2ccccc2)C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.36
MAOA P21397 4/20 0.36
MAOB P27338 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27476971 0.81 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL27858232 0.65 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL28272997 0.64 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL27767618 0.61
SCHEMBL8018747 0.61
SCHEMBL28115541 0.60 KDM1A (0.39) KDM1AMAOAMAOB
SCHEMBL182249 0.58
SCHEMBL27962277 0.58 DRD4 (0.31)
SCHEMBL4331068 0.57 KDM1A (0.67) KDM1AMAOAMAOB
Ammonia Solution, Strong SCHEMBL7586755 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060013843-A1 Cosmetic composition comprising a defined silicone polymer and a surfactant L'OREAL (FR) 2006-01-19 US claimed
US-20040105827-A1 Use for make-up in particular of a cosmetic composition having a continuous hydrophilic comprising a multilayer goniochromatic pigment L'OREAL (FR) 2004-06-03 US claimed
US-20010051171-A1 Cosmetic use of at least one polyorganosiloxane as a gelling agent and cosmetic composition containing it L'OREAL (FR) 2001-12-13 US claimed
WO-2023111079-A1 PROCESS FOR DYEING KERATIN FIBRES USING A (CO)POLYMER BASED ON ACETOACETATE FUNCTIONS, A CROSSLINKING AGENT, A COLOURING AGENT AND A METAL COMPOUND L'OREAL (FR) 2023-06-22 WO disclosed
WO-2023111081-A1 PROCESS FOR DYEING KERATIN FIBRES USING A COPOLYMER BASED ON ACETOACETATE FUNCTIONS, A CROSSLINKING AGENT, A COLOURING AGENT AND A METAL COMPOUND L'OREAL (FR) 2023-06-22 WO disclosed
EP-3946252-A1 METHOD OF MAKING A COLOR COSMETIC COMPOSITION CONTAINING WAX BLEND ELC Management LLC (US) 2022-02-09 EP disclosed
EP-3946251-A1 COLOR COSMETIC COMPOSITION CONTAINING WAX BLEND ELC Management LLC (US) 2022-02-09 EP disclosed
US-20200306168-A1 Color Cosmetic Composition Containing Wax Blend ELC MANAGEMENT LLC 2020-10-01 US disclosed
US-20200306155-A1 Method Of Making A Color Cosmetic Composition Containing Wax Blend ELC MANAGEMENT LLC 2020-10-01 US disclosed
WO-2020198548-A1 METHOD OF MAKING A COLOR COSMETIC COMPOSITION CONTAINING WAX BLEND ELC MANAGEMENT LLC (US) 2020-10-01 WO disclosed
WO-2020198547-A1 COLOR COSMETIC COMPOSITION CONTAINING WAX BLEND ELC MANAGEMENT LLC (US) 2020-10-01 WO disclosed
US-20030143275-A1 Cosmetic and/or dermatological composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer L'OREAL (FR) 2003-07-31 US disclosed
US-20030133889-A1 Use of a composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylmidazole polymer or copolymer L'OREAL (FR) 2003-07-17 US disclosed
US-20030083388-A1 Heat-induced gelling foaming composition and foam obtained L'OREAL (FR) 2003-05-01 US disclosed
US-20030059392-A1 Composition for topical use containing a diblock polymer L'OREAL (FR) 2003-03-27 US disclosed
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer L'OREAL (FR) 2003-03-13 US disclosed
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer L'OREAL (FR) 2003-02-20 US disclosed
US-20020192178-A1 Leguminous extract heavy-metal-scavenging anti-pollution agent L'OREAL (FR) 2002-12-19 US disclosed
CN-1358084-A Transfer-resistant composition structured in rigid form by polymer OREAL (FR) 2002-07-10 CN disclosed
US-20010051171-A1 Cosmetic use of at least one polyorganosiloxane as a gelling agent and cosmetic composition containing it L'OREAL (FR) 2001-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030059392-A1 Composition for topical use containing a diblock polymer KRT18, DSG1, CUTA KDM1A 679/4885MAOA 1461/4885MAOB 555/4885
US-20060013843-A1 Cosmetic composition comprising a defined silicone polymer and a surfactant SGMS2, SGMS1, CUTA KDM1A 3021/4885MAOA 980/4885MAOB 1348/4885
US-20030133889-A1 Use of a composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylmidazole polymer or copolymer VEGFA, VCL, CUTA KDM1A 2265/4885MAOA 757/4885MAOB 1444/4885
US-20030036490-A1 Stable composition with high electrolyte content containing an amphiphilic polymer KRT18, DSG1, SCNN1A KDM1A 1848/4885MAOA 3524/4885MAOB 4672/4885
US-20010051171-A1 Cosmetic use of at least one polyorganosiloxane as a gelling agent and cosmetic composition containing it CUTA, LPO, PRDX1 KDM1A 2762/4885MAOA 199/4885MAOB 570/4885
US-20030050201-A1 Cleansing composition containing an amphiphilic polymer UGCG, SGMS1, SGMS2 KDM1A 2612/4885MAOA 3856/4885MAOB 4529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.