Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858592 | 0.84 | ALDH1A1 (0.46) | CYP2C9CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL27858834 | 0.83 | ERCC1 (0.45) | MAPTEGLN1KMT2AMEN1SIGMAR1 | |
| SCHEMBL27858668 | 0.82 | ALDH1A1 (0.45) | CYP2C9CYP2C19KMT2AMEN1POLB | |
| SCHEMBL27858820 | 0.79 | KDM4E (0.49) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL27841073 | 0.78 | MEN1 (0.45) | MAPTKMT2AMEN1SIGMAR1LMNA | |
| SCHEMBL27841067 | 0.76 | MEN1 (0.46) | CYP2C9CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL27841068 | 0.75 | ALDH1A1 (0.46) | CYP2C9CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL27841122 | 0.72 | KDM4E (0.44) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28555863 | 0.71 | CYP2C9 (0.65) | CYP2C9CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL4322092 | 0.71 | CYP2C9 (0.58) | CYP2C9CYP2C19MAPTEGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264740-A | Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators | — | 2011-11-30 | — | — | CN | disclosed |