Phosphoric Acid

Phosphoric Acid

SCHEMBL27859638

Cc1ccccc1-c1ccccc1-c1ccccc1.O=P(O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
TSHR P16473 1/20 0.46
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
PTGS2 P35354 1/20 0.41
ESR2 Q92731 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MCL1 Q07820 1/20 0.41
MAPT P10636 1/20 0.41
ACP3 P15309 1/20 0.41
BCL2L1 Q07817 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
PDCD1 Q15116 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28234488 0.92 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Bicarbonate SCHEMBL1836484 0.88 MCL1 (0.47) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Phosphoric Acid SCHEMBL242260 0.87 ALDH1A1 (0.50) ALDH1A1HPGDCA2PTGS2ACP3
SCHEMBL1556561 0.87 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Ammonia Solution, Strong SCHEMBL28419333 0.85 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Hydrogen Sulfide SCHEMBL27587997 0.85 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Water SCHEMBL7781910 0.85 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A
Phosphoric Acid SCHEMBL1281473 0.85 ALDH1A1 (0.52) ALDH1A1HPGDCA2PTGS2ACP3
Phosphoric Acid SCHEMBL29542627 0.85 ALDH1A1 (0.52) ALDH1A1HPGDCA2PTGS2ACP3
Formic Acid SCHEMBL28667263 0.84 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279852-B Rubber composition for flexible couplings 现代自动车株式会社 2020-07-14 CN claimed
CN-110540683-A Rubber composition for tire and pneumatic tire SUMITOMO RUBBER IND 2019-12-06 CN disclosed
CN-108473649-A High modulus thermoplastic polyurethane 路博润先进材料公司 2018-08-31 CN disclosed
CN-108368226-A CRYSTALLINE HIGH MODULUS THERMOPLASTIC POLYURETHANE 路博润先进材料公司 2018-08-03 CN disclosed
CN-102549500-B Dry film photoresist KOLON INC 2014-04-30 CN disclosed
CN-102549499-B Dry film photoresist KOLON INC 2013-09-11 CN disclosed
CN-102549499-A Dry film photoresist KOLON INC 2012-07-04 CN disclosed
CN-102549500-A Dry film photoresist KOLON INC 2012-07-04 CN disclosed