⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589014 | 0.75 | — | — | |
| SCHEMBL25572094 | 0.72 | — | — | |
| SCHEMBL765210 | 0.70 | — | — | |
| SCHEMBL18245436 | 0.70 | PRMT3 (0.39) | — | |
| SCHEMBL22996398 | 0.69 | — | — | |
| SCHEMBL48539 | 0.69 | — | — | |
| SCHEMBL19272159 | 0.69 | — | — | |
| SCHEMBL14125339 | 0.69 | — | — | |
| SCHEMBL25590398 | 0.69 | — | — | |
| SCHEMBL20143382 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976339-B1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | claimed |
| US-9957264-B2 | Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-01 | — | — | US | claimed |
| CN-105189498-B | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | 默沙东公司 | 2017-06-27 | — | — | CN | claimed |
| US-20160272632-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-09-22 | — | — | US | claimed |
| EP-2976339-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2016-01-27 | — | — | EP | claimed |
| CN-105189498-A | Geminally substituted cyanoethylpyrazolopyridinones as JANUS kinase inhibitors | MERCK SHARP & DOHME | 2015-12-23 | — | — | CN | claimed |
| WO-2014146491-A1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-09-25 | — | — | WO | claimed |
| US-4788248-A | Thermoplastic resins and polyamides compatibilized with polyamide-polyarylate block copolymers | GENERAL ELECTRIC COMPANY (US) | 1988-11-29 | — | — | US | claimed |
| WO-2024130570-A1 | LIGHT EMITTING DIODE AND DISPLAY APPARATUS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |
| US-11912650-B2 | Bakuchiol derivatives, pharmaceutically acceptable salts thereof, and preparation method and use of the same | JIANGXI SHIMEI PHARMACEUTICAL CO., LTD (CN) | 2024-02-27 | — | — | US | disclosed |
| WO-2024011307-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-6-YL-SULFONAMIDE DERIVATIVES FOR THE INHIBITION OF SGK-1 AND TREATMENT OF CANCER | THRYV THERAPEUTICS INC. (CA) | 2024-01-18 | — | — | WO | disclosed |
| EP-4151687-B1 | METALLIZED ARTICLE AND ASSOCIATED POLY(PHENYLENE ETHER) COMPOSITION AND INJECTION-MOLDED ARTICLE | SHPP GLOBAL TECH BV (NL) | 2023-11-29 | — | — | EP | disclosed |
| US-20230338906-A1 | SEPARATION MEMBRANE | NITTO DENKO CORPORATION (JP) | 2023-10-26 | — | — | US | disclosed |
| WO-2023108291-A9 | APELINERGIC MACROCYCLES AND USES THEREOF | SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) | 2023-09-28 | — | — | WO | disclosed |
| US-20050038037-A1 | Platelet adenosine diphosphate receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-02-17 | — | — | US | disclosed |
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| US-20030060474-A1 | Platelet adenosine diphosphate receptor antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-27 | — | — | US | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |
| US-5449737-A | Urethane modified epoxy resin compositions | CIBA-GEIGY CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| US-4055413-A | SULFIDES | THE PROCTER & GAMBLE COMPANY (US) | 1977-10-25 | — | — | US | disclosed |