Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598023 | 0.86 | MAPT (0.42) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL27598018 | 0.83 | TDP1 (0.38) | MAPTKDM4EMEN1KMT2AGRM5 | |
| SCHEMBL27581431 | 0.83 | KCNH2 (0.38) | MAPTGRM5RAB9AALDH1A1HPGD | |
| SCHEMBL27598064 | 0.82 | FGFR1 (0.36) | GRM5FGFR1METAP1ALDH1A1 | |
| SCHEMBL4044214 | 0.80 | MAPT (0.43) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL27598111 | 0.79 | MEN1 (0.38) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL27598088 | 0.79 | CYP2A6 (0.36) | NPC1GRM5RAB9A | |
| SCHEMBL27844383 | 0.77 | FLT3 (0.41) | KDM4EKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL27598043 | 0.77 | RAB9A (0.34) | MAPTKDM4ENPC1GRM5RAB9A | |
| SCHEMBL27861698 | 0.77 | KMT2A (0.41) | MAPTKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |