Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 10/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581432 | 0.92 | GRIA1 (0.39) | GRIA1GRIA3PDE4DGRM5DRD2 | |
| SCHEMBL27598024 | 0.86 | GRM5 (0.36) | GRIA1GRIA3PDE4DGRM5DRD2 | |
| SCHEMBL27861795 | 0.85 | GAA (0.39) | GRIA1GRIA3PDE4DGRM5DRD2 | |
| SCHEMBL27580424 | 0.85 | MEN1 (0.39) | GRIA1GRIA3PDE4DGRM5RAB9A | |
| SCHEMBL27861662 | 0.84 | GRM5 (0.37) | GRIA1GRIA3PDE4DGRM5MAPT | |
| SCHEMBL27844382 | 0.82 | DRD2 (0.48) | GRM5DRD2HTR2AMAPTL3MBTL1 | |
| SCHEMBL27581556 | 0.82 | GRM5 (0.33) | GRIA1GRIA3PDE4DGRM5DRD2 | |
| SCHEMBL4040155 | 0.78 | GRIA1 (0.42) | GRIA1GRIA3PDE4DGRM5DRD2 | |
| SCHEMBL27598030 | 0.77 | CYP2A6 (0.41) | GRM5MAPTRAB9APPP1CAHIF1A | |
| SCHEMBL4041256 | 0.76 | GRIA1 (0.42) | GRIA1GRIA3PDE4DGRM5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |