Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786513 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2788916 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2784747 | 0.82 | TP53 (0.41) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2787968 | 0.81 | TP53 (0.40) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2787064 | 0.81 | TP53 (0.40) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2784882 | 0.81 | TP53 (0.40) | SMN1; SMN2TP53SSTR4 | |
| SCHEMBL2785433 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2TP53SSTR4LMNA | |
| SCHEMBL2785042 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2TP53LMNA | |
| SCHEMBL2785664 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2LMNA | |
| SCHEMBL2767478 | 0.74 | KMT2A (0.53) | SMN1; SMN2TP53SSTR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | claimed |