⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080364 | 0.89 | SLC6A3 (0.36) | — | |
| SCHEMBL2472947 | 0.80 | — | — | |
| Bromide SCHEMBL7626178 | 0.78 | — | — | |
| SCHEMBL2093337 | 0.77 | — | — | |
| SCHEMBL5087896 | 0.75 | TBXAS1 (0.37) | — | |
| SCHEMBL507903 | 0.74 | — | — | |
| SCHEMBL271211 | 0.74 | — | — | |
| SCHEMBL469221 | 0.74 | — | — | |
| SCHEMBL289897 | 0.74 | HDAC8 (0.40) | — | |
| SCHEMBL14124538 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-222445396-U | Distillation equipment for 5-hydroxymethyl thiazole | 兰州鸿瑄科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-116375662-B | Efficient purification process of 5-hydroxymethyl thiazole pharmaceutical intermediate | 新沂市砥研医药技术研究院有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-117966225-B | QFP blister copper electroplating solution, preparation method and electroplating method | 昆山一鼎工业科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-117966225-A | QFP blister copper electroplating solution, preparation method and electroplating method | 昆山一鼎工业科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116375662-A | Efficient purification process of 5-hydroxymethyl thiazole pharmaceutical intermediate | 新沂市砥研医药技术研究院有限公司 | 2023-07-04 | — | — | CN | claimed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | claimed |
| CN-115521735-B | Adhesive for label paper of daily chemical product packaging bottle and preparation method thereof | 柏仁新材料(广州)股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-115521735-A | Adhesive for label paper of daily chemical product packaging bottle and preparation method thereof | 柏仁新材料(广州)股份有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-115475583-A | Preparation method of expandable microspheres for improving water resistance of microspheres | 快思瑞科技(上海)有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-114213358-A | Synthetic method of 2-bromo-5-formaldehyde thiazole | 上海泰坦科技股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| EP-1624897-B1 | HIV PRODRUGS CLEAVABLE BY CD26 | TIBOTEC PHARM LTD (IE) | 2007-10-10 | — | — | EP | claimed |
| US-20070015743-A1 | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | US | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| CN-1803782-A | Method for synthesizing 4-methyl-5-methyol thiazole | UNIV ZHEJIANG TECHNOLOGY (CN) | 2006-07-19 | — | — | CN | claimed |
| EP-0793659-B1 | PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE | ABBOTT LAB (US) | 2001-03-14 | — | — | EP | claimed |
| WO-1998045279-A1 | PREPARATION OF THIAZOLES USING 1,3-DIHALOPROPENES | REILLY INDUSTRIES, INC. (US) | 1998-10-15 | — | — | WO | claimed |
| US-5780638-A | Process for the preparation of 5-hydroxymethylthiazole | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | claimed |
| US-5712400-A | Process for preparation of 5-hydroxymethylthiazole | ABBOTT LABORATORIES (US) | 1998-01-27 | — | — | US | claimed |
| EP-0793659-A1 | PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE | Abbott Laboratories (US) | 1997-09-10 | — | — | EP | claimed |
| WO-1996016050-A1 | PROCESS FOR PREPARATION OF 5-HYDROXYMETHYLTHIAZOLE | ABBOTT LABORATORIES (US) | 1996-05-30 | — | — | WO | claimed |