Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592179 | 0.75 | POLB (0.47) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL27788485 | 0.75 | POLB (0.39) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL27322913 | 0.72 | POLB (0.41) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL27529146 | 0.72 | POLB (0.44) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL27515999 | 0.71 | CYP2D6 (0.40) | POLBKDM4ENAPRTTSHRADRA1A | |
| SCHEMBL28687108 | 0.71 | POLB (0.40) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL1521276 | 0.69 | POLB (0.48) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL1889093 | 0.68 | ADORA3 (0.47) | POLBKDM4EHSP90AA1NAPRTHCAR2 | |
| SCHEMBL28860220 | 0.66 | TRIM24 (0.32) | KDM4EHSP90AA1 | |
| Ampyzine SCHEMBL30627403 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110352256-A | The technique for leaching metal sulfide with the reagent with thiocarbonyl functionality | 不列颠哥伦比亚大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-107532229-A | Process for leaching metal sulphides with an agent having a thiocarbonyl function | 不列颠哥伦比亚大学 | 2018-01-02 | — | — | CN | disclosed |
| CN-107519168-A | A kind of application of NRF2 inhibitor and its related compound treatment tuberculosis infection | 中国医科大学 | 2017-12-29 | — | — | CN | disclosed |
| CN-102574788-A | Indole derivatives as crac modulators | HOFFMANN LA ROCHE | 2012-07-11 | — | — | CN | disclosed |