Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515999 | 0.75 | CYP2D6 (0.40) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL28140113 | 0.72 | — | — | |
| SCHEMBL6274810 | 0.68 | KDM4E (0.34) | TRIM24TRIM33KDM4EMEN1NPC1 | |
| SCHEMBL14315568 | 0.67 | — | — | |
| SCHEMBL27740550 | 0.67 | ALDH1A1 (0.34) | — | |
| SCHEMBL27862268 | 0.66 | POLB (0.39) | KDM4EHSP90AA1 | |
| SCHEMBL28322497 | 0.66 | — | — | |
| SCHEMBL27768292 | 0.65 | CHRM5 (0.42) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL27803600 | 0.63 | ALDH1A1 (0.39) | KDM4EMEN1NPC1HSP90AA1RAB9A | |
| SCHEMBL1760047 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137571-A | P2X7Inhibitors of receptors | H.隆德贝克有限公司 | 2018-06-08 | — | — | CN | disclosed |