Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 6/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 4/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879717 | 0.85 | GPR119 (0.38) | NOD2NOD1TP53SMN1; SMN2LMNA | |
| SCHEMBL10002989 | 0.83 | NOD2 (0.62) | NOD2NOD1MAPTLMNAKDM4E | |
| SCHEMBL27863415 | 0.82 | NOD2 (0.48) | NOD2NOD1SMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL10003338 | 0.82 | NOD2 (0.61) | NOD2NOD1MAPTLMNAKDM4E | |
| SCHEMBL27863451 | 0.82 | NOD2 (0.48) | NOD2NOD1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27879728 | 0.80 | NOD2 (0.46) | NOD2NOD1TP53SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL27863418 | 0.80 | NOD2 (0.62) | NOD2NOD1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10004083 | 0.76 | NOD2 (0.68) | NOD2NOD1MAPTLMNAKDM4E | |
| SCHEMBL28799514 | 0.74 | NOD2 (0.41) | NOD2NOD1SMN1; SMN2MAPTLMNA | |
| SCHEMBL27963104 | 0.73 | NOD2 (0.39) | NOD2NOD1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574836-B | Aminopyrazole Derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2014-04-16 | — | — | CN | disclosed |
| CN-102574836-A | Aminopyrazole Derivatives | CHUGAI PHARMACEUTICAL CO LTD | 2012-07-11 | — | — | CN | disclosed |