Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953588 | 0.87 | ANO1 (0.55) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1898575 | 0.86 | MEN1 (0.52) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL27863802 | 0.86 | MEN1 (0.47) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL14803098 | 0.85 | ANO1 (0.47) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1907196 | 0.82 | ANO1 (0.51) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL27846763 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1953086 | 0.81 | ANO1 (0.52) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1951216 | 0.81 | MEN1 (0.52) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1907536 | 0.81 | RAB9A (0.49) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL1954046 | 0.81 | LMNA (0.49) | MEN1KMT2ANPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102256969-A | Compounds that modulate intracellular calcium | CALCIMEDICA INC | 2011-11-23 | — | — | CN | disclosed |