SCHEMBL27864263

SCHEMBL27864263

O=Cc1cc(C(=O)O)nn1-c1ccc(C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RPA1 P27694 5/20 0.49
SMN1; SMN2 Q16637 2/20 0.46
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.43
PPP1CA P62136 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.40
PTGS1 P23219 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27520726 0.87 RPA1 (0.59) RPA1SMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL27864272 0.84 RPA1 (0.45) RPA1SMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL27868556 0.83 GAA (0.56) SMN1; SMN2KMT2AMEN1ALDH1A1POLB
SCHEMBL28842592 0.79 RPA1 (0.52) RPA1SMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL27847109 0.77 MEN1 (0.41) SMN1; SMN2KMT2AMEN1ALDH1A1POLB
SCHEMBL27522939 0.73 MAPT (0.63) RPA1KMT2AMEN1ALDH1A1POLB
SCHEMBL27411918 0.73 CA1 (0.47) RPA1ALDH1A1PPP1CAPTGS1
SCHEMBL27864284 0.72 PTGER1 (0.43) RPA1SMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL7428175 0.69 HCAR2 (0.40) RPA1SMN1; SMN2ALDH1A1POLBPPP1CA
SCHEMBL31420268 0.68 L3MBTL1 (0.51) SMN1; SMN2KMT2AMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102405036-B Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2013-09-18 CN claimed
CN-102405036-A Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2012-04-04 CN claimed
CN-110200836-A Hair colourant compositions, method and the box set comprising the composition 诺赛尔股份有限公司 2019-09-06 CN disclosed
CN-104411293-A Hair colorant compositions comprising 2-methoxymethyl-1, 4-diaminobenzene and 2, 6-dihydroxyethylaminotoluene, methods and kits comprising the same PROCTER & GAMBLE 2015-03-11 CN disclosed
CN-104394841-A Hair colorant compositions comprising 2-methoxymethyl-1, 4-diaminobenzene and 5-amino-4-chloro-o-cresol, methods and kits comprising the same PROCTER & GAMBLE 2015-03-04 CN disclosed
CN-104394842-A Hair colorant compositions comprising 2-methoxymethyl-1, 4-diaminobenzene and 2, 6-diaminopyridine, methods and kits comprising the same PROCTER & GAMBLE 2015-03-04 CN disclosed
CN-104394840-A Hair colorant compositions comprising 2-methoxymethyl-1, 4-diaminobenzene, methods and kits comprising the same PROCTER & GAMBLE 2015-03-04 CN disclosed
CN-104334154-A Hair colorant compositions comprising 3-amino 2,6 dimethylphenol, methods, and kits comprising the compositions PROCTER & GAMBLE 2015-02-04 CN disclosed
CN-104168876-A Hair colorant compositions comprising amino -2,6- dimethylphenol and 1,4- phenylenediamine-type developers, methods, and kits comprising the compositions PROCTER 2014-11-26 CN disclosed
CN-102405036-B Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2013-09-18 CN disclosed
CN-102405036-A Keratin dyeing compositions comprising free radical scavengers and uses thereof PROCTER & GAMBLE 2012-04-04 CN disclosed