Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233947 | 0.81 | KDM4E (0.35) | HCAR2KDM4EGRNSORT1BAZ2B | |
| SCHEMBL15784496 | 0.80 | MAPK1 (0.39) | KDM4EBAZ2BALDH1A1POLB | |
| SCHEMBL15300178 | 0.76 | CYP1A2 (0.44) | KDM4EPOLBGAASMN1; SMN2 | |
| SCHEMBL2152111 | 0.74 | HCAR2 (0.41) | HCAR2KDM4EGRNSORT1BAZ2B | |
| SCHEMBL222289 | 0.74 | BAZ2B (0.63) | HCAR2KDM4EGRNSORT1BAZ2B | |
| SCHEMBL70171 | 0.74 | KDM4E (0.58) | HCAR2KDM4EGRNSORT1BAZ2B | |
| SCHEMBL1777981 | 0.73 | KMO (0.35) | KDM4EGAA | |
| SCHEMBL22551724 | 0.73 | ALDH1A1 (0.44) | KDM4EGRNSORT1BAZ2BALDH1A1 | |
| SCHEMBL27847111 | 0.73 | BCL2 (0.36) | HCAR2ALDH1A1APOBEC3AGAAAPOBEC3G | |
| SCHEMBL1430738 | 0.73 | APAF1 (0.36) | HCAR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102405036-B | Keratin dyeing compositions comprising free radical scavengers and uses thereof | PROCTER & GAMBLE | 2013-09-18 | — | — | CN | claimed |
| CN-102405036-A | Keratin dyeing compositions comprising free radical scavengers and uses thereof | PROCTER & GAMBLE | 2012-04-04 | — | — | CN | claimed |
| CN-102405036-B | Keratin dyeing compositions comprising free radical scavengers and uses thereof | PROCTER & GAMBLE | 2013-09-18 | — | — | CN | disclosed |
| CN-102405036-A | Keratin dyeing compositions comprising free radical scavengers and uses thereof | PROCTER & GAMBLE | 2012-04-04 | — | — | CN | disclosed |
| EP-1003748-A2 | PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE | GLAXO GROUP LIMITED (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999012933-A2 | PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE | GLAXO GROUP LIMITED (GB) | 1999-03-18 | — | — | WO | disclosed |