Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7711566 | 0.96 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL7920692 | 0.91 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL2785848 | 0.91 | PPARG (0.46) | PPARGPPARADRD4 | |
| SCHEMBL7922719 | 0.89 | PPARG (0.48) | PPARGPPARADRD4 | |
| Trifluoroacetic Acid SCHEMBL7705739 | 0.88 | PPARG (0.43) | PPARGPPARA | |
| SCHEMBL4609088 | 0.86 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL7168302 | 0.85 | ITGB3 (0.59) | PPARG | |
| SCHEMBL7168299 | 0.85 | ITGB3 (0.59) | PPARG | |
| SCHEMBL377531 | 0.84 | PPARG (0.66) | PPARGPPARA | |
| SCHEMBL377363 | 0.84 | PPARG (0.66) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300129-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2011-12-08 | — | — | US | disclosed |
| WO-2010075037-A1 | SYSTEMS AND METHODS FOR ENHANCING VACCINE EFFICACY | UNIVERSITY OF ROCHESTER (US) | 2010-07-01 | — | — | WO | disclosed |