Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168299 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BITGAVPPARGMAPT | |
| SCHEMBL2786491 | 0.85 | PPARG (0.53) | PPARG | |
| Trifluoroacetic Acid SCHEMBL7711566 | 0.83 | PPARG (0.50) | PPARG | |
| SCHEMBL7920692 | 0.82 | PPARG (0.50) | PPARG | |
| SCHEMBL7922719 | 0.82 | PPARG (0.48) | ITGB3ITGA2BPPARG | |
| SCHEMBL2808625 | 0.82 | PPARG (0.60) | PPARG | |
| Bromide SCHEMBL7424338 | 0.81 | ATM (0.47) | ITGB3ITGA2BITGAV | |
| SCHEMBL2787232 | 0.80 | ITGB1 (0.47) | PPARG | |
| SCHEMBL2787228 | 0.80 | ITGB1 (0.47) | PPARG | |
| SCHEMBL4153373 | 0.79 | PPARG (0.69) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541497-B1 | Amino acid derivatives of benzoxazin-2-ylaminoalkoxyphenylalkyl compounds | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-6353027-B1 | ENANTIOMORPHIC AMINE DERIVATIVES FOR TREATMENT OF DIABETES | ELI LILLY AND COMPANY | 2002-03-05 | — | — | US | disclosed |
| US-6194446-B1 | NON-INSULIN DEPENDENT DIABETES | ELI LILLY AND COMPANY | 2001-02-27 | — | — | US | disclosed |