Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919196 | 0.88 | ESR1 (0.56) | ESR1ESR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL23306974 | 0.81 | ESR1 (0.44) | ESR1ESR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL27844716 | 0.78 | ALDH1A1 (0.67) | ALDH1A1TSHRHSD17B10TDP1KDM4E | |
| SCHEMBL1918994 | 0.76 | ESR1 (0.48) | ESR1ESR2ALDH1A1TSHRKDM4E | |
| SCHEMBL28100731 | 0.76 | KMT2A (0.44) | ESR1ESR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL1921149 | 0.76 | KMT2A (0.44) | ESR1ESR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL1921150 | 0.76 | KMT2A (0.44) | ESR1ESR2ALDH1A1KDM4EKMT2A | |
| SCHEMBL2669826 | 0.74 | NPC1 (0.49) | ESR1ESR2ALDH1A1TSHRKDM4E | |
| SCHEMBL2658573 | 0.74 | ESR1 (0.50) | ESR1ESR2ALDH1A1TSHRHSD17B10 | |
| Pyrrolidine SCHEMBL17338894 | 0.71 | ESR1 (0.36) | ESR1ESR2ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102292316-A | Glucagon antagonists | — | 2011-12-21 | — | — | CN | disclosed |