Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881404 | 0.87 | GSK3B (0.49) | ERCC5FEN1PARP15PARP14PARP10 | |
| SCHEMBL19339679 | 0.83 | ERCC5 (0.48) | ERCC5FEN1TNKSPARP15PARP14 | |
| SCHEMBL27865108 | 0.82 | ERCC5 (0.47) | ERCC5FEN1TNKSPARP15PARP14 | |
| SCHEMBL203505 | 0.81 | TNKS (0.58) | ERCC5FEN1TNKSPARP15PARP14 | |
| SCHEMBL5312318 | 0.79 | ERCC5 (0.67) | ERCC5FEN1TNKSPARP15PARP14 | |
| SCHEMBL27865128 | 0.78 | GSK3B (0.50) | GSK3BHDAC8PTPN1 | |
| SCHEMBL695598 | 0.76 | GSK3B (0.43) | ERCC5FEN1TNKSPARP15PARP14 | |
| SCHEMBL753074 | 0.72 | GSK3B (0.50) | ERCC5FEN1PARP15PARP14PARP10 | |
| SCHEMBL1542192 | 0.69 | GSK3B (0.53) | GSK3BMAPTPTPN1NPC1POLB | |
| SCHEMBL29440418 | 0.69 | GSK3B (0.53) | GSK3BMAPTPTPN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596936-A | Antiviral compounds | GILEAD SCIENCES INC | 2012-07-18 | — | — | CN | disclosed |