Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 9/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307699 | 0.91 | GSK3B (0.52) | GSK3BPTPN1KMT2A | |
| SCHEMBL695598 | 0.86 | GSK3B (0.43) | GSK3BPTPN1ERCC5FEN1SRD5A2 | |
| SCHEMBL27881404 | 0.84 | GSK3B (0.49) | GSK3BPTPN1ERCC5FEN1SRD5A2 | |
| SCHEMBL204218 | 0.82 | GSK3B (0.70) | GSK3BPTPN1ERCC5FEN1PARP10 | |
| SCHEMBL1758965 | 0.77 | PTPN1 (0.51) | GSK3BPTPN1 | |
| SCHEMBL27881403 | 0.77 | GSK3B (0.51) | GSK3BPTPN1ERCC5FEN1SRD5A2 | |
| SCHEMBL1350830 | 0.75 | GSK3B (0.67) | GSK3BPTPN1ERCC5FEN1SRD5A2 | |
| SCHEMBL8260473 | 0.75 | GSK3B (0.77) | GSK3BPTPN1ERCC5FEN1SRD5A2 | |
| SCHEMBL1701352 | 0.75 | LTA4H (0.46) | SRD5A2PARP10KMT2A | |
| SCHEMBL21495038 | 0.75 | LTA4H (0.46) | SRD5A2PARP10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |