Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11763275 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SYKHTTLTA4HKMT2A | |
| SCHEMBL27567814 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SYKHTTLTA4HKMT2A | |
| SCHEMBL27706533 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SYKLTA4HKMT2AMAPK1 | |
| SCHEMBL11169957 | 0.86 | ALDH1A1 (0.45) | ALDH1A1SYKHTTLTA4HKMT2A | |
| SCHEMBL27703130 | 0.86 | ALDH1A1 (0.45) | ALDH1A1SYKHTTLTA4HKMT2A | |
| SCHEMBL28761645 | 0.86 | ALDH1A1 (0.42) | ALDH1A1SYKLTA4HKMT2AMAPK1 | |
| SCHEMBL28796022 | 0.85 | LMNA (0.42) | ALDH1A1SYKLTA4HKMT2AMAPK1 | |
| SCHEMBL27697836 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SYKLTA4HKMT2AMAPK1 | |
| SCHEMBL6016191 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SYKLTA4HKMT2AMAPK1 | |
| SCHEMBL27703135 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SYKLTA4HKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020961-A | Antiviral compound | 吉利德制药有限责任公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-104230900-B | Antiviral compound | 吉利德制药有限责任公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-106588890-A | Antiviral compounds | 吉利德制药有限责任公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-104016971-B | Antiviral compound | PHARMASSET INC. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-104230900-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-24 | — | — | CN | disclosed |
| CN-104211689-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-17 | — | — | CN | disclosed |
| CN-104211713-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-17 | — | — | CN | disclosed |
| CN-104016971-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-09-03 | — | — | CN | disclosed |
| CN-102596936-B | Antiviral compounds | GILEAD SCIENCES INC | 2014-06-11 | — | — | CN | disclosed |
| CN-102596936-A | Antiviral compounds | GILEAD SCIENCES INC | 2012-07-18 | — | — | CN | disclosed |