Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804826 | 0.90 | PDE2A (0.39) | PDE2A | |
| SCHEMBL30095837 | 0.90 | PDE2A (0.39) | PDE2A | |
| SCHEMBL30748233 | 0.89 | — | — | |
| SCHEMBL2189832 | 0.86 | ADORA3 (0.43) | PDE2AHSP90AA1TRAP1HSP90AB1ALDH1A1 | |
| SCHEMBL25876283 | 0.85 | PDE1A (0.44) | PDE1APDE1BPDE1CPDE2ANPC1 | |
| SCHEMBL17926576 | 0.85 | HSP90AA1 (0.39) | PDE2AHSP90AA1TRAP1HSP90AB1ALDH1A1 | |
| SCHEMBL7919917 | 0.83 | CYP1A2 (0.39) | PDE2AHSP90AA1TRAP1HSP90AB1KMT2A | |
| SCHEMBL21282879 | 0.81 | SRC (0.45) | PDE1APDE1BPDE1CABL1 | |
| SCHEMBL16981657 | 0.79 | PDE9A (0.44) | PDE1CPDE2AHSP90AA1TRAP1 | |
| SCHEMBL31051055 | 0.79 | PDE9A (0.44) | PDE1CPDE2AHSP90AA1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |