SCHEMBL2804826

SCHEMBL2804826

CCCCn1ncc2c(Cl)nc(Cl)nc21

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30095837 1.00 PDE2A (0.39) PDE2A
SCHEMBL30748233 0.95
SCHEMBL2786539 0.90 PDE1A (0.42) PDE2A
SCHEMBL30095946 0.85 PDE2A (0.37) PDE2A
SCHEMBL28701258 0.85 HSP90AA1 (0.49)
SCHEMBL2189832 0.83 ADORA3 (0.43) PDE2A
SCHEMBL17926576 0.82 HSP90AA1 (0.39) PDE2A
SCHEMBL7919917 0.81 CYP1A2 (0.39) PDE2A
SCHEMBL30748211 0.81
SCHEMBL25690422 0.80 MPO (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010118367-A2 ANTIVIRAL PYRIMIDINES PROGENICS PHARMACEUTICALS, INC. (US) 2010-10-14 WO disclosed