Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752821 | 0.93 | ESR2 (0.45) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL29012841 | 0.85 | BACE1 (0.44) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL27881924 | 0.83 | ESR2 (0.38) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL27865604 | 0.83 | NPC1 (0.36) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL13453553 | 0.82 | ESR2 (0.43) | ESR2GRIA4TBK1USP30 | |
| SCHEMBL19107642 | 0.81 | QDPR (0.51) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL27865603 | 0.81 | ESR2 (0.42) | ESR2NPC1TBK1GBA1 | |
| SCHEMBL24790803 | 0.77 | PLG (0.40) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL17397793 | 0.76 | QDPR (0.46) | ESR2NPC1PKMRAB9AALDH1A1 | |
| SCHEMBL18663813 | 0.75 | ESR2 (0.46) | ESR2ALDH1A1LMNASSTR4TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596874-A | Cyclic compound, method for producing same, radiation-sensitive composition, and method for forming resist pattern | MITSUBISHI GAS CHEMICAL CO | 2012-07-18 | — | — | CN | disclosed |