Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580981 | 0.92 | ESR2 (0.45) | ESR2USP30HRH3AKR1A1AKR1B1 | |
| SCHEMBL13602803 | 0.85 | ESR2 (0.43) | ESR2AKR1A1AKR1B1 | |
| SCHEMBL14302792 | 0.83 | ESR2 (0.38) | ESR2USP30 | |
| SCHEMBL27865627 | 0.82 | ESR2 (0.44) | ESR2TBK1USP30GRIA4 | |
| SCHEMBL9625514 | 0.81 | ESR2 (0.45) | ESR2FASNTBK1 | |
| SCHEMBL9625511 | 0.81 | ESR2 (0.45) | ESR2FASNTBK1 | |
| SCHEMBL14302796 | 0.81 | CYP2C9 (0.48) | ESR2USP30 | |
| Hydrochloric Acid SCHEMBL29953377 | 0.79 | QDPR (0.46) | ESR2 | |
| SCHEMBL27865603 | 0.79 | ESR2 (0.42) | ESR2FASNTBK1 | |
| SCHEMBL9979948 | 0.79 | ESR2 (0.52) | ESR2FASNUSP30GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678431-B2 | Photostable liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-03-16 | — | — | US | disclosed |