Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179687 | 0.90 | KDM4E (0.43) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL1443193 | 0.90 | MAPT (0.46) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL1442780 | 0.90 | F2 (0.44) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL27882033 | 0.88 | HTR1A (0.47) | HTR1ADRD2MAPTMEN1KMT2A | |
| SCHEMBL1442495 | 0.88 | HTR1A (0.52) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL10178956 | 0.88 | MAPT (0.55) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10179432 | 0.88 | HCRTR1 (0.41) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL27882087 | 0.88 | WNT3A (0.44) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL1443398 | 0.87 | HTR1A (0.54) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL1442833 | 0.86 | HTR1A (0.52) | HTR1ADRD2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596932-A | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors | BAYER SCHERING PHARMA AG | 2012-07-18 | — | — | CN | claimed |