Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 9/20 | 0.40 |
| ▸ | DRD3 | P35462 | 9/20 | 0.40 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007890 | 0.86 | MAPT (0.41) | MAPT | |
| SCHEMBL21704250 | 0.80 | MAPT (0.50) | MAPTGBA1CYP2D6 | |
| SCHEMBL2271581 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL3601179 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL17048017 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL3597729 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL3601182 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL3597725 | 0.78 | MAPT (0.65) | MAPTGBA1DRD2DRD3 | |
| SCHEMBL28046374 | 0.77 | HPGD (0.48) | MAPTDRD2DRD3DRD1 | |
| SCHEMBL4058697 | 0.77 | GBA1 (0.47) | GBA1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102432525-A | Practical synthesis method of 3-benzyl-3-azabicyclo [2,1,0] hexane | SUZHOU KANGRUN PHARMACEUTICALS INC | 2012-05-02 | — | — | CN | claimed |
| CN-104402791-B | Preparation method for nebracetam | 河南师范大学 | 2017-02-01 | — | — | CN | disclosed |
| CN-104402791-B | Preparation method for nebracetam | 河南师范大学 | 2017-02-01 | — | — | CN | disclosed |
| CN-104402791-A | Preparation method for nebracetam | UNIV HENAN NORMAL | 2015-03-11 | — | — | CN | disclosed |
| CN-102432525-A | Practical synthesis method of 3-benzyl-3-azabicyclo [2,1,0] hexane | SUZHOU KANGRUN PHARMACEUTICALS INC | 2012-05-02 | — | — | CN | disclosed |