Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27790899 | 0.81 | GNAI3 (0.36) | GNAI3GNAO1GNAI1TDP1SOS1 | |
| Tert-Butyl Formate SCHEMBL27764923 | 0.81 | KCNH2 (0.49) | GNAI3GNAO1GNAI1TDP1SOS1 | |
| SCHEMBL14376953 | 0.80 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| Tert-Butyl Formate SCHEMBL27722708 | 0.80 | TDP1 (0.41) | GNAI3GNAO1GNAI1TDP1 | |
| Tert-Butyl Formate SCHEMBL27757049 | 0.80 | GNAI3 (0.37) | GNAI3GNAO1GNAI1TDP1SOS1 | |
| Tert-Butyl Formate SCHEMBL27701072 | 0.76 | TDP1 (0.43) | GNAI3GNAO1GNAI1TDP1EP300 | |
| Tert-Butyl Formate SCHEMBL27410595 | 0.76 | TDP1 (0.46) | TDP1EPHX1SSTR1SSTR4 | |
| Tert-Butyl Formate SCHEMBL27987725 | 0.76 | TDP1 (0.46) | GNAI3GNAO1GNAI1TDP1EPHX1 | |
| Tert-Butyl Formate SCHEMBL27591602 | 0.76 | TDP1 (0.46) | GNAI3GNAO1GNAI1TDP1EP300 | |
| Tert-Butyl Formate SCHEMBL27852871 | 0.74 | TDP1 (0.45) | TDP1EPHX1SSTR1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102448958-B | Pyrimidyl and 1,3,5-triazines base benzimidazole sulfonamides and its purposes in cancer therapy | VETDC, INC. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-102448958-A | Pyrimidinyl and 1,3, 5-triazinyl benzimidazole sulfonamides and their use in the treatment of cancer | PATHWAY THERAPEUTICS LTD | 2012-05-09 | — | — | CN | disclosed |