Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13087302 | 0.85 | EGFR (0.72) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2880220 | 0.85 | MAPT (0.70) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL2808606 | 0.78 | MAPT (0.74) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1391173 | 0.78 | EGFR (0.79) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9316001 | 0.78 | LMNA (0.47) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL13087238 | 0.78 | KMT2A (0.60) | EGFRMAPTKMT2AMEN1MAPK1 | |
| SCHEMBL1390891 | 0.77 | EGFR (0.73) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL31744573 | 0.76 | EGFR (0.64) | EGFRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL10997330 | 0.76 | MAPT (0.56) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL1390779 | 0.76 | MAPT (1.00) | EGFRMAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |