Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2808606 | 0.86 | MAPT (0.74) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL2786809 | 0.85 | EGFR (0.71) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL2880220 | 0.79 | MAPT (0.70) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL31744573 | 0.77 | EGFR (0.64) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL7256671 | 0.76 | KMT2A (0.52) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL1390891 | 0.75 | EGFR (0.73) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL31620286 | 0.75 | ALDH1A1 (0.55) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL27798554 | 0.74 | KMT2A (0.48) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL1391173 | 0.74 | EGFR (0.79) | EGFRLMNAMAPTALDH1A1KMT2A | |
| SCHEMBL31620269 | 0.73 | PDE5A (0.63) | EGFRLMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |