SCHEMBL27869166

SCHEMBL27869166

CCCC(C)Oc1cccc(Cl)n1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 4/20 0.48
L3MBTL1 Q9Y468 1/20 0.35
CCR5 P51681 3/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
DRD4 P21917 1/20 0.32
IDH1 O75874 6/20 0.31
IDH2 P48735 5/20 0.31
CCNB2 O95067 1/20 0.30
CCNE2 O96020 1/20 0.30
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30
CCNB3 Q8WWL7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27852178 0.90 MCHR1 (0.40) MCHR1L3MBTL1CCR5ALDH1A1GAA
SCHEMBL27852165 0.86 MCHR1 (0.45) MCHR1L3MBTL1ALDH1A1GAASMN1; SMN2
SCHEMBL27869169 0.82 MCHR1 (0.38) MCHR1L3MBTL1CCR5CYP3A4TSHR
SCHEMBL27869215 0.81 L3MBTL1 (0.38) MCHR1L3MBTL1CCR5ALDH1A1GAA
SCHEMBL19121588 0.81 MCHR1 (0.46) MCHR1CCR5TSHR
SCHEMBL425129 0.78 L3MBTL1 (0.40) MCHR1L3MBTL1ALDH1A1GAASMN1; SMN2
SCHEMBL27852208 0.78 MCHR1 (0.37) MCHR1L3MBTL1DRD4
SCHEMBL27852276 0.77 MCHR1 (0.45) MCHR1L3MBTL1ALDH1A1CYP3A4TSHR
SCHEMBL28794497 0.77 MCHR1 (0.35) MCHR1L3MBTL1CCR5ALDH1A1GAA
SCHEMBL20780129 0.77 MCHR1 (0.35) MCHR1L3MBTL1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102452978-A 2-chloro-substituted or unsubstituted aliphatic hydrocarbyloxypyridine and method for producing same CHONGQING KANGDING MEDICAL TECHNOLOGY CO LTD 2012-05-16 CN disclosed