Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | IDH2 | P48735 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523502 | 0.84 | KMT2A (0.42) | MCHR1TSHRALDH1A1SMN1; SMN2GRM5 | |
| SCHEMBL27869168 | 0.84 | MCHR1 (0.42) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL27852165 | 0.81 | MCHR1 (0.45) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL27869215 | 0.80 | L3MBTL1 (0.38) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL19510740 | 0.80 | IDH1 (0.42) | L3MBTL1CYP3A4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL363302 | 0.79 | CYP3A4 (0.38) | L3MBTL1CYP3A4TSHRALDH1A1IDH1 | |
| SCHEMBL27852276 | 0.79 | MCHR1 (0.45) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL27869174 | 0.78 | L3MBTL1 (0.35) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL27869166 | 0.78 | MCHR1 (0.48) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 | |
| SCHEMBL28794497 | 0.78 | MCHR1 (0.35) | L3MBTL1MCHR1CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283921-A1 | DPD INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 北京深蓝泰医药科技有限公司 | 2023-01-19 | — | — | WO | claimed |
| CN-107567443-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-28 | — | — | CN | disclosed |
| CN-115925679-A | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2023-04-07 | — | — | CN | disclosed |
| EP-3239143-B1 | BIARYL DERIVATIVE AS GPR120 AGONIST | LG CHEMICAL LTD (KR) | 2023-03-22 | — | — | EP | disclosed |
| US-20220135574-A1 | BIARYL DERIVATIVE AS GPR120 AGONIST | LG CHEM, LTD. (KR) | 2022-05-05 | — | — | US | disclosed |
| US-11261186-B2 | Biaryl derivative as GPR120 agonist | LG CHEM. LTD. (KR) | 2022-03-01 | — | — | US | disclosed |
| CN-105392777-B | Biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2020-09-22 | — | — | CN | disclosed |
| EP-3013796-B9 | BIARYL DERIVATIVES AS GPR120 AGONISTS | LG CHEMICAL LTD (KR) | 2020-07-01 | — | — | EP | disclosed |
| EP-3628661-A1 | BIARYL DERIVATIVES AS GPR120 AGONISTS | LG CHEM, LTD. (KR) | 2020-04-01 | — | — | EP | disclosed |
| US-10221138-B2 | Biaryl derivatives as GPR120 agonists | LG CHEM, LTD. (KR) | 2019-03-05 | — | — | US | disclosed |
| CN-105392777-A | Biaryl derivatives as GRP120 agonists | LG LIFE SCIENCES LTD | 2016-03-09 | — | — | CN | disclosed |
| WO-2014209034-A1 | BIARYL DERIVATIVES AS GPR120 AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2014-12-31 | — | — | WO | disclosed |
| CN-102452978-A | 2-chloro-substituted or unsubstituted aliphatic hydrocarbyloxypyridine and method for producing same | CHONGQING KANGDING MEDICAL TECHNOLOGY CO LTD | 2012-05-16 | — | — | CN | disclosed |
| EP-2417121-A1 | 4, 5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | Pfizer Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| US-20120022058-A1 | 4,5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | PFIZER INC. | 2012-01-26 | — | — | US | disclosed |
| WO-2010116282-A1 | 4, 5-DIHYDRO-LH-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | PFIZER INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| CN-1084735-C | Substituted pyridin-2-ones and substituted pyridine-2-thiones as biocides | ARCH CHEMICAL INDUSTRY CO (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1133035-A | Substituted pyridin-2-ones and substituted pyridine-2-thiones as biocides | OLIN CORP (US) | 1996-10-09 | — | — | CN | disclosed |
| US-4529800-A | Novel process for the preparation of 2-halo-3-nitro-6-alkoxy-pyridines | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-07-16 | — | — | US | disclosed |
| EP-0102652-A1 | Method for the preparation of pure 2-chloro-6-alkoxy-3-nitro-pyridines | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1984-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135574-A1 | BIARYL DERIVATIVE AS GPR120 AGONIST | GPR119, GLP1R, GIPR | L3MBTL1 2990/4885MCHR1 587/4885CYP3A4 1149/4885 |
| US-10221138-B2 | Biaryl derivatives as GPR120 agonists | GPR119, GLP1R, GIPR | L3MBTL1 3522/4885MCHR1 588/4885CYP3A4 1368/4885 |
| US-20120022058-A1 | 4,5-DIHYDRO-1H-PYRAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USES | NR3C2, REN, AGTR1 | L3MBTL1 4869/4885MCHR1 1932/4885CYP3A4 753/4885 |
| US-11261186-B2 | Biaryl derivative as GPR120 agonist | GPR119, GPR88, FFAR1 | L3MBTL1 4242/4885MCHR1 530/4885CYP3A4 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.