Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727034 | 0.84 | HRH3 (0.44) | ALDH1A1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL17177230 | 0.83 | HRH3 (0.46) | ALDH1A1ALOX15KMT2ATDP1HRH3 | |
| SCHEMBL1088574 | 0.80 | BAZ2A (0.49) | ALDH1A1BAZ2ASIGMAR1ALOX15MEN1 | |
| SCHEMBL553090 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1BAZ2AALOX15MEN1KMT2A | |
| SCHEMBL2929353 | 0.80 | KDM4E (0.45) | ALDH1A1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL25145880 | 0.76 | BAZ2A (0.41) | ALDH1A1BAZ2ASIGMAR1ALOX15MEN1 | |
| SCHEMBL27324746 | 0.76 | BAZ2A (0.44) | ALDH1A1BAZ2ASIGMAR1ALOX15MEN1 | |
| SCHEMBL4914482 | 0.76 | BAZ2A (0.44) | ALDH1A1BAZ2ASIGMAR1ALOX15MEN1 | |
| SCHEMBL27324327 | 0.76 | BAZ2A (0.44) | ALDH1A1BAZ2ASIGMAR1ALOX15MEN1 | |
| SCHEMBL4914470 | 0.76 | KMT2A (0.53) | ALDH1A1BAZ2AMEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687880-B | Cysteine protease inhibitors | MEDIVIR AB | 2012-09-05 | — | — | CN | disclosed |