Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18306589 | 0.77 | BAZ2A (0.43) | BAZ2ASCN1ASCN8AALDH1A1HRH3 | |
| SCHEMBL1088574 | 0.76 | BAZ2A (0.49) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL27870171 | 0.76 | ALDH1A1 (0.45) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL21917001 | 0.73 | HRH4 (0.42) | BAZ2ASIGMAR1MEN1KMT2APLAT | |
| SCHEMBL8114045 | 0.73 | BAZ2A (0.46) | BAZ2AALOX15PLATCTSBCTSS | |
| SCHEMBL25145880 | 0.73 | BAZ2A (0.41) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL4914482 | 0.73 | BAZ2A (0.44) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL4914470 | 0.73 | KMT2A (0.53) | BAZ2AMEN1KMT2AALDH1A1CTSL | |
| SCHEMBL27324327 | 0.73 | BAZ2A (0.44) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL25146002 | 0.71 | PDE10A (0.35) | BAZ2AALOX15SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |