Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25145880 | 0.85 | BAZ2A (0.41) | BAZ2AALOX15SIGMAR1MEN1KMT2A | |
| SCHEMBL12786862 | 0.82 | LMNA (0.57) | BAZ2ALMNATP53TSHRSTAT1 | |
| SCHEMBL1088574 | 0.80 | BAZ2A (0.49) | BAZ2ALMNATSHRALOX15SIGMAR1 | |
| SCHEMBL31532426 | 0.78 | CYP2D6 (0.38) | BAZ2ALMNATP53TSHRSTAT1 | |
| SCHEMBL27870171 | 0.76 | ALDH1A1 (0.45) | BAZ2ALMNAALOX15SIGMAR1MEN1 | |
| SCHEMBL4914470 | 0.76 | KMT2A (0.53) | BAZ2AMEN1KMT2AALDH1A1CTSL | |
| SCHEMBL4914482 | 0.76 | BAZ2A (0.44) | BAZ2ALMNAALOX15SIGMAR1MEN1 | |
| SCHEMBL2339833 | 0.74 | CNR2 (0.58) | BAZ2ALMNATSHRALDH1A1CTSL | |
| Hydrochloric Acid SCHEMBL1929103 | 0.73 | CNR2 (0.57) | BAZ2ALMNATSHRALDH1A1CTSL | |
| SCHEMBL346976 | 0.73 | BAZ2A (0.45) | BAZ2AMEN1KMT2ACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |