SCHEMBL27870232

SCHEMBL27870232

CC(=O)CC(O)(O)C(C)=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
TRPA1 O75762 1/20 0.35
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
LMNA P02545 1/20 0.30
SLC15A2 Q16348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15755909 0.79 ALDH1A1 (0.40) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL10001246 0.75 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL1669880 0.75 ALDH1A1 (0.38) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL1056782 0.73
SCHEMBL11439849 0.73 ALDH1A1 (0.41) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL12836892 0.73 ALDH1A1 (0.40) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL11397668 0.71
SCHEMBL28494 0.71
SCHEMBL10571434 0.71 ALDH1A1 (0.39) ALDH1A1TDP1TRPA1HMGCRCHRM1
SCHEMBL7041938 0.71 HMGCR (0.58) ALDH1A1TDP1TRPA1HMGCRCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110498782-A A kind of continuous preparation method of 2,5- dimethyl -4- hydroxyl -3 (2H) furanone XIAMEN OAMIC BIOTECH CO LTD 2019-11-26 CN claimed
CN-109879742-A A kind of preparation method of 3,4- dihydroxy -2,5- acetyl butyryl 安徽金禾实业股份有限公司 2019-06-14 CN claimed
CN-102452915-B Preparation method of 3,4-dihydroxy-2,5-hexanedione SHANGHAI WANXIANG DAILY CHEMICAL CO LTD 2014-07-09 CN claimed
CN-110498782-A A kind of continuous preparation method of 2,5- dimethyl -4- hydroxyl -3 (2H) furanone XIAMEN OAMIC BIOTECH CO LTD 2019-11-26 CN disclosed
CN-110372646-A A kind of preparation method of furanone 安徽金轩科技有限公司 2019-10-25 CN disclosed
CN-109879742-A A kind of preparation method of 3,4- dihydroxy -2,5- acetyl butyryl 安徽金禾实业股份有限公司 2019-06-14 CN disclosed
CN-102452915-B Preparation method of 3,4-dihydroxy-2,5-hexanedione SHANGHAI WANXIANG DAILY CHEMICAL CO LTD 2014-07-09 CN disclosed
CN-102452915-A Preparation method of 3, 4-dihydroxy-2, 5-hexanedione SHANGHAI WANXIANG DAILY CHEMICAL CO LTD 2012-05-16 CN disclosed