Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Resorcinol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL10554522 | 0.85 | CA2 (0.58) | CA12CA2CA9CA14LMNA | |
| Phloroglucinol SCHEMBL28571198 | 0.85 | GLRA1 (0.59) | CA12CA2CA9CA14LMNA | |
| Resorcinol SCHEMBL8654067 | 0.83 | ALDH1A1 (0.60) | CA12CA2CA9ALDH1A1CA14 | |
| Succinic Acid SCHEMBL8655758 | 0.83 | ALDH1A1 (0.60) | CA12CA2CA9ALDH1A1CA14 | |
| Phenol SCHEMBL28330103 | 0.83 | CA2 (0.55) | CA12CA2CA9CA14LMNA | |
| Resorcinol SCHEMBL21409924 | 0.83 | ALDH1A1 (0.60) | CA12CA2CA9ALDH1A1CA14 | |
| 3-Hydroxybenzaldehyde SCHEMBL8212584 | 0.82 | UNG (0.50) | KDM4EFFAR1 | |
| Resorcinol SCHEMBL27758291 | 0.82 | CA12 (0.67) | CA12CA2CA9ALDH1A1CA14 | |
| Resorcinol SCHEMBL27365108 | 0.82 | ALDH1A1 (0.52) | CA12CA2CA9ALDH1A1CA14 | |
| Resorcinol SCHEMBL5404097 | 0.82 | ALDH1A1 (0.75) | CA12CA2CA9ALDH1A1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103536594-A | Application of G-protein-coupled receptor antagonist in preparing medicine for treating glutamate receptor high-expression tumor | JIANGSU YAHONG MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-102638979-A | O-benzyl nicotinamide analogs as mGluR5 positive allosteric modulators | UNIV VANDERBILT | 2012-08-15 | — | — | CN | disclosed |