O-Xylene

O-Xylene

SCHEMBL27872004

CCCCOC(=O)NN.Cc1ccccc1C

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
HSD17B10 Q99714 2/20 0.53
TSHR P16473 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
SMN1; SMN2 Q16637 9/20 0.50
CYP1A2 P05177 4/20 0.50
CYP2C19 P33261 4/20 0.50
RAB9A P51151 10/20 0.49
NPC1 O15118 9/20 0.49
HPGD P15428 5/20 0.49
CYP2C9 P11712 2/20 0.49
LMNA P02545 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
MAPK1 P28482 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
STAT1 P42224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27872109 0.94 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
O-Xylene SCHEMBL27872009 0.94 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
O-Xylene SCHEMBL27872007 0.94 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
O-Xylene SCHEMBL27872003 0.94 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
SCHEMBL283132 0.84
Hydrazine SCHEMBL28106872 0.82 EPHX1 (0.53) ALDH1A1TSHRSMN1; SMN2RAB9ANPC1
Acetic Acid Butyl Ester SCHEMBL6809657 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL30919973 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10TSHRTDP1L3MBTL1
SCHEMBL13506223 0.79 SMN1; SMN2 (0.68) ALDH1A1L3MBTL1SMN1; SMN2CYP1A2CYP2C19
SCHEMBL722043 0.79 EPHX1 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471244-B Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI CHEMICAL CORP 2014-09-24 CN disclosed
CN-103588680-A Composition for transfer and storage of N-substituted carbamic acid ester and isocyanate production method ASAHI KASEI CHEMICALS CORP 2014-02-19 CN disclosed
CN-103553972-A Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester ASAHI KASEI CHEMICALS CORP 2014-02-05 CN disclosed
CN-103097348-A Process for producing carbonyl compounds ASAHI KASEI CHEMICALS CORP (JP) 2013-05-08 CN disclosed
CN-102471244-A Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI KASEI CHEMICALS CORP (JP) 2012-05-23 CN disclosed