O-Xylene

O-Xylene

SCHEMBL27872109

CCCCCCCOC(=O)NN.Cc1ccccc1C

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 2/20 0.55
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
TSHR P16473 3/20 0.54
LMNA P02545 3/20 0.54
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
EPHX1 P07099 1/20 0.51
CYP3A4 P08684 2/20 0.51
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
MAPT P10636 2/20 0.47
ACHE P22303 6/20 0.46
ESR1 P03372 1/20 0.46
MEN1 O00255 1/20 0.46
NR1I2 O75469 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27872007 1.00 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4EPOLBTSHR
O-Xylene SCHEMBL27872009 1.00 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4EPOLBTSHR
O-Xylene SCHEMBL27872003 1.00 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4EPOLBTSHR
O-Xylene SCHEMBL27872004 0.94 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EPOLBTSHR
SCHEMBL28764612 0.85 EPHX1 (0.68) TSHREPHX1ACHE
SCHEMBL28848111 0.85 EPHX1 (0.68) TSHREPHX1ACHE
SCHEMBL723173 0.85 EPHX1 (0.68) TSHREPHX1ACHE
SCHEMBL721745 0.85 EPHX1 (0.68) TSHREPHX1ACHE
SCHEMBL10878591 0.85 EPHX1 (0.68) TSHREPHX1ACHE
SCHEMBL18641585 0.85 EPHX1 (0.68) TSHREPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471244-B Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI CHEMICAL CORP 2014-09-24 CN disclosed
CN-103588680-A Composition for transfer and storage of N-substituted carbamic acid ester and isocyanate production method ASAHI KASEI CHEMICALS CORP 2014-02-19 CN disclosed
CN-103553972-A Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester ASAHI KASEI CHEMICALS CORP 2014-02-05 CN disclosed
CN-103097348-A Process for producing carbonyl compounds ASAHI KASEI CHEMICALS CORP (JP) 2013-05-08 CN disclosed
CN-102471244-A Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI KASEI CHEMICALS CORP (JP) 2012-05-23 CN disclosed