Diethyl Pyrocarbonate

Diethyl Pyrocarbonate

SCHEMBL27872608

C=CC(=O)O.CCOC(=O)OC(=O)OCC

nearest known ligand 0.68

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.68
ALDH1A1 P00352 6/20 0.52
LMNA P02545 2/20 0.46
HCAR2 Q8TDS4 1/20 0.45
TSHR P16473 4/20 0.42
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 2/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
TRPA1 O75762 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
GLO1 Q04760 1/20 0.34
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethyl Pyrocarbonate SCHEMBL30366210 0.83 SOAT1 (1.00) SOAT1ALDH1A1LMNAHCAR2TSHR
Diethyl Pyrocarbonate SCHEMBL15582 0.83 SOAT1 (1.00) SOAT1ALDH1A1LMNAHCAR2TSHR
SCHEMBL7076343 0.82 SOAT1 (0.61) SOAT1ALDH1A1LMNAHCAR2TSHR
Acrylic Acid SCHEMBL29212705 0.81 LMNA (0.50) SOAT1ALDH1A1LMNAHCAR2TSHR
SCHEMBL7096132 0.80 SOAT1 (0.65) SOAT1ALDH1A1LMNAHCAR2TSHR
Hydrochloric Acid SCHEMBL28853305 0.80 SOAT1 (0.58) SOAT1ALDH1A1LMNAHCAR2TSHR
SCHEMBL11470775 0.80 SOAT1 (0.58) SOAT1ALDH1A1LMNAHCAR2TSHR
Diethyl Pyrocarbonate SCHEMBL3815029 0.80 SOAT1 (0.94) SOAT1ALDH1A1LMNAHCAR2TSHR
Diethyl Pyrocarbonate SCHEMBL28670714 0.80 SOAT1 (0.94) SOAT1ALDH1A1LMNAHCAR2TSHR
SCHEMBL28247811 0.80 SOAT1 (0.94) SOAT1ALDH1A1LMNAHCAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102438447-A Safening agent TAMINCO NV 2012-05-02 CN disclosed