SCHEMBL2787280

SCHEMBL2787280

Cc1ccc2c(c1C)Cc1cc3[nH]c4ccccc4c3cc1-2

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.47
AHR P35869 1/20 0.45
CA1 P00915 11/20 0.44
CA2 P00918 11/20 0.44
CA4 P22748 11/20 0.44
CA6 P23280 11/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPT P10636 1/20 0.43
ATM Q13315 1/20 0.43
PGR P06401 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19916051 0.81 KIF11 (0.49) KIF11AHRCA1CA2CA4
SCHEMBL30631720 0.78 KIF11 (0.56) KIF11AHRCA1CA2CA4
SCHEMBL11992353 0.78 KIF11 (0.56) KIF11AHRCA1CA2CA4
Carbazole SCHEMBL29015265 0.78 CA1 (0.47) CA1CA2CA4CA6KDM4E
SCHEMBL17206856 0.76 KIF11 (0.53) KIF11AHRCA1CA2CA4
SCHEMBL20165853 0.74 CA1 (0.59) CA1CA2CA4CA6
SCHEMBL30116551 0.72 KIF11 (0.56) KIF11AHRCA1CA2CA4
SCHEMBL11992354 0.72 KIF11 (0.56) KIF11AHRCA1CA2CA4
SCHEMBL21692091 0.71 KIF11 (0.60) KIF11AHRCA1CA2CA4
SCHEMBL25612670 0.71 CYP1A2 (0.39) KDM4EMAPTPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010136109-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed