SCHEMBL27872806

SCHEMBL27872806

CCNC1(NCC)c2cc(C=O)ccc2-c2ccc(N(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 2/20 0.36
ALDH1A1 P00352 1/20 0.36
ALDH3A1 P30838 1/20 0.36
NR3C2 P08235 1/20 0.32
PDK2 Q15119 1/20 0.32
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2A13 Q16696 1/20 0.31
MEN1 O00255 1/20 0.31
PSMD14 O00487 1/20 0.31
APAF1 O14727 1/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
MMP2 P08253 1/20 0.31
RAD52 P43351 1/20 0.31
CASP6 P55212 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781069 0.83 ALDH1A1 (0.38) ALDH1A3ALDH1A1ALDH3A1PDK2HDAC3
SCHEMBL13372219 0.83 ALDH1A1 (0.37) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL14427916 0.81 ALDH1A1 (0.35) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL14427943 0.79 PDK2 (0.36) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL19052322 0.79 IP6K1 (0.38) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL28355417 0.77 MMP2 (0.36) ALDH1A3ALDH1A1ALDH3A1HDAC3HDAC1
SCHEMBL6775885 0.77 MMP2 (0.36) ALDH1A3ALDH1A1ALDH3A1HDAC3HDAC1
SCHEMBL14427946 0.77 ALDH1A1 (0.33) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL13357071 0.76 PDK2 (0.39) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6
SCHEMBL13805748 0.75 ALDH1A1 (0.40) ALDH1A3ALDH1A1ALDH3A1PDK2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102712663-A Novel organic electroluminescent compounds and organic electroluminescent device using the same DOW ADVANCED DISPLAY MAT LTD 2012-10-03 CN disclosed