Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11299920 | 0.86 | HTR2A (0.59) | SPHK1HTR2AHTR2CHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL11146240 | 0.86 | HTR2A (0.59) | SPHK1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL7772142 | 0.82 | SLC6A3 (0.61) | HTR2AHTR2CHTR7HTR6KCNH2 | |
| Oxalic Acid SCHEMBL10465317 | 0.82 | HTR2A (0.61) | SPHK1HTR2AHTR2CKCNH2SIGMAR1 | |
| SCHEMBL27805513 | 0.81 | HRH3 (0.54) | SPHK1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL7031548 | 0.81 | HRH3 (0.62) | HTR2AHTR2CHTR7HTR6KCNH2 | |
| SCHEMBL10902405 | 0.81 | MEN1 (0.67) | HTR2AKCNH2SIGMAR1EBP | |
| SCHEMBL13556830 | 0.81 | SPHK1 (0.63) | SPHK1HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL2741683 | 0.81 | HRH3 (0.62) | HTR2AHTR2CHTR7HTR6KCNH2 | |
| Hydrochloric Acid SCHEMBL7447525 | 0.81 | SLC6A3 (0.59) | HTR2AHTR2CHTR7HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712626-B | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-102712626-A | Piperazine compounds having PGDS inhibitory effect | TAIHO PHARMACEUTICAL CO LTD | 2012-10-03 | — | — | CN | disclosed |