Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7447525 | 0.98 | SLC6A3 (0.59) | SLC6A3HRH3SIGMAR1L3MBTL1MBTD1 | |
| SCHEMBL7031548 | 0.98 | HRH3 (0.62) | SLC6A3HRH3SIGMAR1L3MBTL1MBTD1 | |
| SCHEMBL2741683 | 0.98 | HRH3 (0.62) | SLC6A3HRH3SIGMAR1L3MBTL1MBTD1 | |
| Hydrochloric Acid SCHEMBL223935 | 0.97 | HRH3 (0.61) | SLC6A3HRH3SIGMAR1L3MBTL1MBTD1 | |
| Hydrochloric Acid SCHEMBL6596661 | 0.88 | LTA4H (0.59) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL4767153 | 0.88 | SIGMAR1 (0.63) | HRH3SIGMAR1CYP1A2CYP3A4MEN1 | |
| SCHEMBL22386773 | 0.88 | LTA4H (0.59) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL2741684 | 0.88 | LTA4H (0.59) | HRH3SIGMAR1KCNH2 | |
| SCHEMBL10902405 | 0.88 | MEN1 (0.67) | SLC6A3SIGMAR1EBPMEN1KMT2A | |
| SCHEMBL7453093 | 0.87 | HRH3 (0.61) | SLC6A3HRH3SIGMAR1L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160030441-A1 | NIACIN MIMETICS, AND METHODS OF USE THEREOF | ARISAPH PHARMACEUTICALS, INC. | 2016-02-04 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160030441-A1 | NIACIN MIMETICS, AND METHODS OF USE THEREOF | NAMPT, NNT, NAPRT | SLC6A3 303/4885HRH3 1233/4885SIGMAR1 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.